The goal of this function is to help understand how changes in splicing profile affect the protein function in the cell. Two lists of genomic regions are expected: one list of regions of interest, and another serves as the control. A typical input can be a list of alternatively spliced exons or junctions identified by an RNA-seq experiments as the "target", and a list of expressed but not alternatively spliced exons or junctions in the same experiment as the "background", although generally any regions meaningful for the user can be used. The tool compares the frequency of predicted protein features overlapping with regions in each list and performs an enrichment analysis.
Please consult the help page for more information.
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Please select one (recommended) or more prediction tool(s) from the following list.
To start exploring, choose only Pfam.
Please note that each tool is designed to predict a different set of features of the protein sequence. A detailed description of the tools can be found at InterPro website. Choosing multiple tools may produce redundancy in the result if they are designed to predict similar features.
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